Biological Resource Centre (BRC)
Annotated samples of clinical, biological, genealogical or epidemiological data represent an exceptional resource on which the research work of tomorrow's medicine is based.
Missions
It guarantees optimal conditions for the preparation and storage of samples, following the french standard of quality.
The BRC must encourage the use of biocollections, their sharing and collaboration between research teams.
Premises and equipment
The BRC is equipped with :
- offices, one of which is dedicated to the reception of samples
- two laboratories: a type L2 laboratory for the preparation of samples under sterile conditions (serum, plasma, cells, urine, etc.) and a laboratory for the extraction of nucleic acids (DNA and RNA) and the aliquoting of stools
- an air-conditioned room housing refrigerators and freezers for preservation at +4°C, -25°C and -80°C (maximum capacity of 24 chambers)
- a secure cryogenics room equipped with 330-litre liquid nitrogen tanks, with automatic filling, for conservation at -196°C (maximum capacity of 6 tanks)
Sample Safety
- the temperature of the storage chambers is recorded 24 hours a day, 7 days a week;
- a double monitoring system allows immediate intervention to secure the samples in case of failure (on-call personnel);
- emergency chambers are always available (1 for 5);
- access to the premises is controlled (badge access).
Quality Process
Date Base
- the complete traceability of a sample from its reception to its delivery
- management of :
- collections
- donor data
- donor consents
- data relating to the sample itself
- the availability of samples
- collaborations
- contracts
- monitoring of the BRC's activities
As the BRC is multi-thematic, it cannot manage all the clinical-biological data related to the various collections. This management is the responsibility of the scientific managers of the collections, who generally have databases specific to their themes.
How to contact us
institut de biologie
9 quai Moncousu - 44093 Nantes Cedex 1, France
Tel : +33 253 48 22 02